Biosafety and Biosecurity Guidelines

Toxins

Experiments involving the deliberate formation of recombinant or synthetic nucleic acid molecules containing genes for the biosynthesis of toxin molecules lethal for vertebrates at an LD50 of less than 100 nanograms per kilogram of body weight (see Section III-B of the NIH Guidelines)

Major Actions

The deliberate transfer of a drug resistance trait to a microorganism when such resistance could compromise the ability to control the disease agent in humans, veterinary medicine, or agriculture (see Section III-A-1-a of the NIH Guidelines)

Lentiviral containment

Use of CRISPR/Cas941

Human Gene Transfer

Guidelines for handling human material (Clinical BRF Guide)

Animal Experiments

Stem Cell Information

Incident Reporting

Dual Use of Research Concern Guidance (DURC)

Enrollment for required safety trainings